Harvard Health Content API

Certain drugs, supplements, or foods can interact with common heart medications. Known as drug-drug or drug-nutrient interactions, these can occur at any point of the drug’s “life cycle:” absorption, metabolism, or excretion. When a drug or other substance alters the absorption or metabolism of another drug, this may reduce or increase its effects. For example, grapefruit juice can elevate blood levels of certain statins and potentially increase the risk of side effects.

A gene editing technique that permanently shuts down a cholesterol-raising protein called PCSK9 is being tested in heart attack survivors with an inherited form of high cholesterol. The one-time infusion contains tiny particles that contain the editing tools, which travel through the blood to the liver and changes the cells that produce the protein. If early data show the treatment to be safe and effective, the therapy potentially could be used in people who have “garden variety” high cholesterol.

Running can boost cardiovascular fitness faster and better than walking, but this high-impact activity comes with a higher risk of injuries than walking. Beginning runners should start slow and alternate walking and running at first. Doing strength training and increasing mileage gradually may help. People who sustain minor injuries when running should rest for a few days and consult a physical therapist if the injury doesn’t get better.

A coronary artery calcium scan (often called a calcium scan) uses a special type of CT scan to look for calcium deposits in the lining of the heart’s arteries. The results can help people decide whether to start taking a statin.

In addition to raising blood pressure, too much salt in the diet can have other detrimental effects on the heart, including damaging the inner layer of blood vessels and altering the body’s hormonal and inflammatory response. Following the DASH diet, choosing lower-sodium versions of commonly eaten foods, and skipping the saltshaker can help people eat less salt. To boost flavor without salt, options include salt-free herb and spice blends, lemon or lime zest or juice, and flavored vinegars.