Harvard Health Content API

Gut bacteria may influence our emotions and cognitive capabilities. For example, some bacteria make oxytocin, a hormone the body produces that encourages increased social behavior. Other bacteria make substances that cause symptoms of depression and anxiety. Still others make substances that help people to be calmer under stress. Gut bacteria also have been shown to influence people’s vulnerability to certain brain diseases, including Alzheimer’s disease, Parkinson’s disease, and autism. For example, a substance found in the brains of people with Parkinson’s disease (synuclein) is made by gut bacteria and can travel via nerves from the gut to the brain.

Studies suggest that the world is facing two different dementia trends. One is that dementia rates are falling steadily in the United States and Europe. The other is that the number of dementia cases globally is rising, and will likely triple in the next 30 years, mostly due to population increases. People can try to reduce their dementia risk by adopting a healthy lifestyle that includes lots of exercise, a healthy diet, at least seven hours of sleep per night, limited alcohol consumption, socializing, improved balance, stress management, smoking cessation, and control of underlying health conditions.

High doses of the popular pain reliever acetaminophen (Tylenol) may raise blood pressure when taken for two weeks.

Middle-aged men who often feel worried or anxious may be more prone to problems that raise heart disease risk as they age compared with their less-worried peers.

If most middle-aged and older American adults added just 10 to 20 minutes of moderate exercise to their normal daily activities, it could prevent an estimated 110,000 to 209,000 premature deaths each year.

A plant-based Mediterranean meal featuring vegetables, mushrooms, beans, and whole grains prepared with olive oil is a heart-friendly dinner option.

Up to 10% of people with high blood pressure have secondary hypertension, which is caused by another condition or disease. The most common of these involve problems with the adrenal glands (hyperaldosteronism), or the arteries supplying the kidneys (renal artery stenosis). People most likely to have secondary hypertension include those with resistant hypertension who use three or more medications to manage their blood pressure, and people who develop hypertension before age 30.

Someone who has a transient ischemic attack (TIA, or ministroke) needs prompt testing to look for the underlying cause. A 2022 study shows that people can safely get that evaluation at a specialized outpatient clinic rather than having to be admitted to the hospital. The testing usually includes a heart ultrasound (echocardiogram), cardiac monitoring, and imaging tests. The results guide targeted stroke-prevention treatments, which can reduce the risk of a future stroke by as much as 80%.

The most common cause of a stiff, narrowed aortic valve (aortic stenosis) is a buildup of scar tissue and calcium on the valve. Factors that contribute to narrowing of this valve include age, an inborn valve defect, and various diseases such as kidney disease. Aortic stenosis can cause shortness of breath, fatigue, and lightheadedness, especially during physical activity.

Experts suggest people replace their walking shoes every 300 to 500 miles. For the best selection and advice, people should consider shopping at a specialty running store that also sells walking shoes. Other tips for choosing comfortable, supportive shoes include looking for low-heeled shoes that bend easily at the ball of the foot and have wiggle room at the toes.