Harvard Health Content API

A 2025 study addressed the role of genes versus lifestyle habits and life circumstances in influencing a person’s health. Researchers found that genes seemed to have a stronger influence than lifestyle and life circumstances for some diseases, including dementia, macular degeneration, and certain cancers. For other diseases, such as atherosclerosis involving arteries of the heart and brain, rheumatoid arthritis, and diseases of the lung, heart, and liver, lifestyle and life circumstances had a stronger influence than genes.

Evidence published in 2025 suggests that 15 million people in the United States are at risk for developing heart failure, a condition in which the heart doesn’t pump well enough to meet the body’s needs. The estimate was determined with improved tools to calculate risk, called the PREVENT equations. Like previous methods, the equations consider age, blood pressure, cholesterol levels, and smoking history. But the PREVENT equations remove race (an unreliable predictor) and add additional aspects of health.

In a 2025 study of about 2,000 people (average age 80) who were followed for seven years, about a third developed dementia or mild cognitive impairment. Being socially active seemed to delay that diagnosis for about five years.

A 2024 study of more than 32,000 depression-free women who were followed for 14 years found that those who ate the most weekly servings of citrus (six or more) had a 22% lower risk for developing depression, compared with those who ate the least citrus.

About 25% of people have a common heart variant called a patent foramen ovale (PFO), a flaplike opening between the heart’s upper chambers. In people with the condition, venous blood can leak across the heart from the right atrium to the left atrium, bypassing the lungs. If that blood contains a clot, it can travel directly to the arteries that send blood throughout the body. A stroke can occur if that clot lodges in an artery supplying the brain. In people prone to blood clots, a PFO raises the risk of stroke and dementia.

A daily serving of cheese is linked to a lower risk of heart disease, stroke, and death from cardiovascular disease. But it’s best to pair cheese with foods like whole-grain crackers or salad instead of combining it with refined carbohydrates and meat, such as cheese on burgers or pizza. Health-promoting fermentation products may counteract the saturated fat and sodium found in cheese.

Substituting potassium-containing salt substitutes for regular salt can help lower blood pressure as well as the risk of stroke. But people should also check the sodium content in foods and eat more potassium-rich produce.

TV medical dramas often portray treatments for heart attacks and cardiac arrest. While the timelines are often accelerated and certain aspects may be dramatized to engage viewers, the medical details are, for the most part, factual and authentic. Writers and producers routinely rely on health care experts — including Harvard doctors — to make sure the information is accurate. For people with heart disease, seeing how emergency physicians treat urgent conditions may show them what to expect.