Harvard Health Content API

Getting vaccinated against influenza (flu), COVID-19, and pneumonia is especially important for people who have cardiovascular disease. The coughing and congestion that commonly occur with respiratory infections can make breathing more difficult, and the potential drop in oxygen puts added stress on the heart. Serious infections sometimes trigger sepsis, which happens when the immune system is overwhelmed or goes into overdrive, causing symptoms such as a rapid heart rate, very fast breathing, and low blood pressure. These complications can lead to a heart attack.

After common heart procedures or surgeries, medications to help prevent heart attacks and strokes are essential. These include a combination of drugs to prevent blood clots (which is known as dual antiplatelet therapy and usually taken for just one year); drugs to lower LDL cholesterol down to 70 milligrams per deciliter or lower; and drugs to keep blood pressure and blood sugar in a healthy range.

A heart disease diagnosis may trigger a bout of depression. But having depression can also leave people more vulnerable to heart disease. Some of the overlap stems from shared lifestyle factors, such as inactivity and an unhealthy diet. In addition to addressing those issues, other safe and effective ways to ease depression include working with a therapist, using a light box, and taking medications.

A 2025 study found that exercising earlier in the day (before 1 p.m.) offered more benefits like better lung and heart health and walking efficiency compared with exercising later in the day (after 4 p.m.).

Eating a variety of flavonoid-rich foods may offer greater protection against cardiovascular disease and cancer than eating only a few high-flavonoid foods, according to a 2025 study.