What has the most impact on longevity?

Studies suggest that genes and lifestyle affect longevity. Harvard researchers found that injecting certain genes into mice protected them from becoming obese and from developing type 2 diabetes, heart failure, and a particular kind of kidney failure. A recent study of worms found that when worms exercise regularly (but not too much) early in life, their metabolism improves, their muscles and guts function better throughout life, they live longer, and they are protected against the worm version of Alzheimer’s disease. Scientists must now learn if the findings translate to humans.