Slightly More Heart Attacks with Pradaxa

People who take a newer blood thinner to prevent strokes may have a slightly higher risk of heart attack, a review of research finds. The overall heart attack rate was small, however. The new review combined results of 7 prior studies. The studies included 20,000 people who used dabigatran (Pradaxa). They were compared with about 10,500 people who used older drugs, warfarin (Coumadin) or enoxaparin (Lovenox). Everyone in these studies had atrial fibrillation. This is a heart rhythm problem that increases formation of blood clots. People were taking blood thinners to prevent strokes caused by a clot. Among those taking dabigatran, 1.2% had a heart attack or had chest pain that occurred with little exertion. For those taking the other drugs, the rate of these heart events was 0.8%.