Gene editing: A one-time fix for dangerously high cholesterol?

A gene editing technique that permanently shuts down a cholesterol-raising protein called PCSK9 is being tested in heart attack survivors with an inherited form of high cholesterol. The one-time infusion contains tiny particles that contain the editing tools, which travel through the blood to the liver and changes the cells that produce the protein. If early data show the treatment to be safe and effective, the therapy potentially could be used in people who have “garden variety” high cholesterol.

Content restricted. Requires subscription