Exercise, metabolism, and weight: New research from <em>The Biggest Loser</em>

Studies of contestants from the TV show The Biggest Loser found that due to changes in metabolism, people who have lost large amounts of weight have to follow an extremely low-calorie diet in order to maintain the weight loss. Subsequent research indicates that these metabolic changes are related to calorie restriction while weight is being lost, but later become a function of sustained physical activity.