Drug May Improve Chronic Constipation

A new drug may help relieve long-term constipation in some people, a new study finds. Researchers tested linaclotide in two studies. Each included about 600 people with chronic (long-lasting) constipation. People in each study were randomly divided into 3 groups. Two groups received linaclotide, but in different doses. The third group took placebo (fake) pills. The study lasted 12 weeks. The goal was for people to have at least 3 bowel movements a week. About 20% of those taking linaclotide achieved that goal. About 3% to 6% of those taking the placebo had this result. The drug also helped to reduce symptoms such as bloating in many people, researchers said. About 15% of those taking linaclotide developed diarrhea. Most of them remained in the study. About 4% dropped out. One of the studies included an extra 4 weeks.