RNA-targeted drugs for heart disease

RNA-targeted drugs work by preventing the synthesis of proteins involved in different diseases. One, called inclisiran (Leqvio), dramatically lowers LDL cholesterol with just two injections per year. Additional RNA-targeted drugs to lower elevated lipoprotein (a) and high blood pressure are currently in late-stage clinical trials.

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The lowdown on vaginal TLC

Substances women eat, drink, or use can support or detract from vaginal health. The vagina’s microbiome includes trillions of healthy bacteria that inhibit harmful bacteria. Certain conditions, such as an infection called bacterial vaginosis, indicate a harmful shift in the vaginal microbiome. Fruits, vegetables, legumes, and whole grains benefit the vagina by tamping down inflammation. Other vagina-friendly foods include yogurt and soy. Staying well hydrated helps ward off dryness. Smoking or douching, however, can harm vaginal health.

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Should I get the shingles vaccine?

The shingles vaccine, Shingrix, can trigger side effects such as a sore arm, achiness, fatigue, and fever. But Shingrix is highly effective at preventing painful shingles rashes and a complication called postherpetic neuralgia, which involves long-lasting nerve pain.

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Rethinking your morning coffee

Coffee and other caffeine sources can interact with many common drugs, changing the way they’re absorbed, distributed through the body, processed, and excreted. Coffee (even decaf) makes stomach contents more acidic, accounting for some drug interactions, but caffeine is mostly the cause. Medications vulnerable to coffee or caffeine’s effects include those for cold or allergy, depression, high blood pressure, asthma, osteoporosis, anemia, Alzheimer’s disease, thyroid problems, and insomnia. Drinking coffee and taking medications at separate times is advised.

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3 kettlebell moves

Kettlebells can add depth to home workouts as they are easily stored and can be used to perform virtually any type of movement for an all-around workout that hits the major muscles. Kettlebells look like balls or bells with handles on top and range in weight from five to 30 pounds and higher. While they can function similarly to dumbbells, kettlebells can provide a more challenging workout, as a person needs muscle strength, balance, core stability, flexibility, and coordination to control its weight.

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