Reaping the rewards of running

Running can boost cardiovascular fitness faster and better than walking, but this high-impact activity comes with a higher risk of injuries than walking. Beginning runners should start slow and alternate walking and running at first. Doing strength training and increasing mileage gradually may help. People who sustain minor injuries when running should rest for a few days and consult a physical therapist if the injury doesn’t get better.

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Gene editing: A one-time fix for dangerously high cholesterol?

A gene editing technique that permanently shuts down a cholesterol-raising protein called PCSK9 is being tested in heart attack survivors with an inherited form of high cholesterol. The one-time infusion contains tiny particles that contain the editing tools, which travel through the blood to the liver and changes the cells that produce the protein. If early data show the treatment to be safe and effective, the therapy potentially could be used in people who have “garden variety” high cholesterol.

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Salt shakedown: How and why you should eat less sodium

In addition to raising blood pressure, too much salt in the diet can have other detrimental effects on the heart, including damaging the inner layer of blood vessels and altering the body’s hormonal and inflammatory response. Following the DASH diet, choosing lower-sodium versions of commonly eaten foods, and skipping the saltshaker can help people eat less salt. To boost flavor without salt, options include salt-free herb and spice blends, lemon or lime zest or juice, and flavored vinegars.

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A mask that’s hard to shed

Melasma, which causes dark patches on the face, is far more prevalent in women than in men. Dubbed the “mask of pregnancy,” melasma triggers include not only pregnancy but also hormonal fluctuations, genetics, and sun exposure. People with darker skin are more prone to it. Melasma is typically treated with topical products that lighten the skin or slough off cells. Laser treatments and chemical peels, however, may worsen melasma. Sunscreen use can help prevent flares.

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