Semaglutide (Ozempic, Wegovy), which mimics a natural hormone called GLP-1, has become a popular obesity drug because it promotes dramatic weight loss. New evidence suggests this drug and others like it may also curb compulsions for things other than food. The drugs may also dampen cravings for alcohol, smoking, gambling, and excessive shopping by hampering activation of the brain’s reward pathways. If further research confirms preliminary findings, the demand for GLP-1 drugs is likely to increase.
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People who are sedentary more than 10 hours per day may have a higher risk of later developing dementia than those who spend less time being inactive, according to a 2023 study.
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An estimated 58 million American adults live with a mental illness such as anxiety, depression, or bipolar disorder. More women than men receive treatment such as medication or counseling. But despite its pervasiveness, mental illness remains stigmatized. Scientific advances are helping dismantle damaging public attitudes about mental illness. People with mental health challenges can help combat stigma by embracing treatment, not taking other people’s offhand comments personally, and sharing their personal stories.
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A 2023 study suggests older adults with vision problems, including up close or at a distance, face significantly higher risks of dementia than those with no vision problems.
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A small randomized trial in 2023 found that taking two 250-mg capsules of curcumin four times a day was as effective at relieving dyspepsia symptoms as taking one daily 20-mg dose of the heartburn medication omeprazole (Prilosec, Zegerid).
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Both loneliness and isolation were associated with poor health outcomes in a 2023 study. However, social isolation was a stronger predictor of physical decline and early death, while loneliness was more predictive of mental health issues such as depression.
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In a 2023 study, people who didn’t exercise regularly but accumulated three and a half minutes of vigorous daily activity (such as stair climbing) had a 32% lower risk for developing cancer, compared with non-exercisers who didn’t do any vigorous activity.
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Drinking excessive amounts of alcohol and feasting on foods high in natural compounds called purines may trigger gout in some people. Purine-rich foods that might be found on a holiday buffet include roast beef, brisket, lamb or pork chops, veal, chicken liver, turkey, trout, haddock, scallops, oysters, mussels, lobster, shrimp, or crab. While it’s not necessary to completely shun alcohol and foods high in purines, doctors advise limiting them and sticking to a plant-based diet when possible, even during the holidays.
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Continuous positive airway pressure (CPAP) is a first-line treatment for people with obstructive sleep apnea. The CPAP keeps the airway open by pushing a forceful stream of air through a tube and into a mask worn during sleep. The air comes from a small bedside pump (an air compressor). Other forms of positive airway pressure (PAP) may be helpful for people with central sleep apnea. Doctors determine which type of PAP therapy and device someone needs. Patients select the type of PAP mask to use with the system.
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Abruptly stopping a medication can be risky and even life-threatening. For example, suddenly discontinuing certain drugs can cause a rebound effect, meaning that symptoms or problems that were controlled—such as high blood pressure or heartburn—can return with a vengeance. Stopping some medications, such as prescription painkillers or antidepressants, might result in withdrawal symptoms. Before quitting any drug cold turkey, it’s important to consult with a doctor to make sure that it’s safe.
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