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Clinical trials are under way using gene therapy to treat inherited cardiovascular conditions, including familial hypercholesterolemia (one form of abnormally high cholesterol), hypertrophic cardiomyopathy (a type of heart muscle disease), and transthyretin amyloid cardiomyopathy (a form of heart failure resulting from amyloid deposits). But challenges remain in developing and delivering these therapies.
Compared with analog scales, digital scales are more accurate and easier to read. Many smart scales include added features such as smartphone connectivity and body composition estimates.
Tiny mesh tubes called stents, used to prop open heart arteries, can relieve stable angina (chest pain with exertion or emotional stress) in many people with coronary artery disease. But this treatment—which carries a risk of complications and a high cost—should be reserved only for people who don’t get relief from drug therapy. Stents do not prevent future heart attacks or improve survival compared with drug therapy. Angina usually results from arteries that are more than 70% blocked, but most heart attacks occur in arteries that are narrowed by only about 40% or less but harbor plaque that ruptures without warning. The resulting blood clot blocks blood flow, triggering a heart attack.
The PREVENT equation is a new online calculator to predict a person’s odds of developing heart disease. Compared to previous calculators, the updated tool considers broader measures of health (including biomarkers for kidney and metabolic health) and a longer age span (starting at 30 instead of 40 years of age). The goal is to encourage earlier, more targeted strategies to help people avoid cardiovascular problems.
A 2023 study suggests excessive TV-watching, defined as four or more hours a day, is associated with higher risk of developing brain-based disorders such as dementia, depression, and Parkinson’s disease.
A 2023 study suggests replacing a daily serving of processed meats with whole grains, nuts, or beans is associated with lower odds of cardiovascular conditions such as heart attack or stroke.
A 2023 study suggests that moving, standing, or even sleeping are all better than sitting for people’s weight, waistlines, and heart health.
Uterine fibroids affect up to 80% of women by age 50. These noncancerous growths can shrink as menopause approaches and the body’s estrogen level falls. But for some women, fibroids grow during and after the transition to menopause, worsening symptoms such as heavy bleeding, pelvic or lower back pain, bloating, frequent urination, or painful sex. Treatments for other health conditions may also influence older women’s fibroid symptoms. To avert cancer concerns, doctors may remove fibroids that grow noticeably after menopause.
Forgiveness is defined by replacing ill will toward an offender with goodwill. A 2023 study suggests forgiveness boosts mental health by reducing depression and anxiety levels. Other evidence suggests physical benefits as well. Studies indicate forgiveness also eases stress, improves sleep, and lowers blood pressure and heart rate. Being unable to forgive can raise blood pressure, which can affect overall heart health. Some people are innately better at forgiving, but Harvard experts say all people can learn skills that help them forgive.
Back pain symptoms can vary widely, ranging from a dull, ongoing ache to intense, shooting pain or spasms. Often, back pain is due to pulls or strains in muscles and soft tissues. Other times, it’s caused by inflammation or problems with spinal discs or bones. Most cases of muscular back pain ease with time and home-based treatments such as gentle movement, anti-inflammatory pain relievers, and heat and ice. Physical therapy to strengthen core muscles can also help. People whose back pain is severe or doesn’t resolve after three to four weeks should see a doctor.