Gut check: How the microbiome may mediate heart health

The trillions of bacteria in a person’s intestines, called the gut microbiota, may mediate some of the risk factors that affect cardiovascular health. Some bacteria break down cholesterol. Others create compounds that regulate blood pressure, affect hormones involved in diabetes, and dampen inflammation. But the feasibility of changing a person’s microbiome remains unclear, which means any potential microbiome-based therapies for heart disease are still years away.