Eyes, Falls May Offer Alzheimer’s Clues

Frequent falls or protein deposits in the eye could signal an increased risk of Alzheimer’s disease, two studies suggest. Both were presented at a conference in France. The fall study included 125 people with normal brain function. Their average age was 74. Journals they kept showed that 48 fell at least once in a 6-month period. Everyone was given a spinal tap to look for substances that can detect Alzheimer’s risk. People with these substances in their spinal fluid were much more likely to fall than others. The eye study compared photographs of the retina for 3 groups. These included 13 people with Alzheimer’s and 13 with mild cognitive impairment. This condition can lead to Alzheimer’s. The third group consisted of 110 healthy people. Blood vessels in people with Alzheimer’s were narrower. This showed they had a protein buildup in the vessels.

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NSAID Risk Seen for Heart Patients

A new study finds that taking one type of pain reliever long-term may be risky for people with high blood pressure and heart disease. The study focused on nonsteroidal anti-inflammatory drugs (NSAIDs). Some of the most popular over-the-counter pain relievers are NSAIDs. They include ibuprofen (Advil, Motrin and others) and naproxen (Aleve, Naprosyn and others). The group also includes a prescription medicine, celecoxib (Celebrex). The study focused on 882 people who took NSAIDs regularly. They were compared with almost 22,000 people who used these drugs from time to time or never. Everyone in the study had coronary artery disease and high blood pressure. Researchers kept track of them for about 3 years. In that time, the rate of death, heart attack and stroke was 47% higher in regular NSAIDs than in those who used the drugs less or not at all.

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Placebos ‘Improve’ Asthma Symptoms

A fake treatment (placebo) can make asthma patients feel better just as well as a real treatment, a new study suggests. But tests showed the real treatment improved breathing more. The study included 39 asthma patients. Each person visited a doctor’s office 3 times, with a few days between visits. They received treatments each time, in random order. They were treated with a standard albuterol inhaler, a fake inhaler or fake acupuncture. They also were given no treatment sometimes. People also received repeated tests of their ability to exhale. These tests showed 20% improvement with the albuterol inhaler and 7% with the other approaches. But patients thought their breathing improved about 45% to 50% with all three of the active treatments. They thought there was a 21% improvement with no treatment. The study raises many questions about the so-called placebo effect.

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