Longer Tamoxifen Use Cuts Cancer Deaths

Taking a common breast cancer drug longer than usual can further reduce deaths from the disease, a new study says. The research focused on a group of 6,846 women with a type of breast cancer that grows in response to the hormone estrogen. When the study began, they already had taken the drug tamoxifen for 5 years, the standard treatment. Tamoxifen blocks the effects of estrogen on breast cancer. It helps to keep the cancer from returning after surgery. In the study, the women were randomly assigned to stick to standard treatment or to take tamoxifen for another 5 years. By the end of the study, cancer had returned in 25% of women who took the drug for 5 years and 21% of those who took it for 10 years. About 12% of the women who extended tamoxifen treatment died of breast cancer, compared with 15% of the women who stopped after 5 years.