Immune System Suspected in Type 2 Diabetes

New research suggests that type 2 diabetes may result when the immune system makes antibodies against fat cells. The antibodies attack the cells so they can’t use insulin properly. This is called insulin-resistance. Researchers fed mice that weren’t yet insulin-resistant a high-fat diet. After several weeks, the researchers gave some of the mice a drug called anti-CD20 (a drug for humans called rituximab). The rest of the mice (the control group) got no treatment. The drug-treated mice didn’t develop insulin resistance. They had normal blood sugar levels. The other mice all became insulin-resistant. The researchers say that the results suggest the possibility of one day having a vaccine that protects obese people from developing type 2 diabetes. The study was published online April 17 in the journal Nature Medicine. HealthDay News wrote about it on April 17.