Study: Two LDL Drugs No Better Than One

A two-drug cholesterol pill does not protect arteries any better than one drug, a study finds. The pill is called Vytorin. It contains Zocor, a statin drug that lowers LDL cholesterol. It also contains Zetia, which lowers LDL in a different way. People were randomly assigned to take either Zocor or Zocor plus Zetia. Plaque buildup in arteries was about the same in the two groups. This occurred even though the two drugs reduced LDL more than Zocor did. The Associated Press reported on the study March 31. It was presented at a meeting of the American College of Cardiology. It also was published online by the New England Journal of Medicine.

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Melatonin and Dizzy Spells

At least once a week I experience a bout of extreme dizziness. It is accompanied by a physical feeling of being turned upside down, and everything looks upside down and blurred to me. It is very sudden and random. My body feels very heavy when this happens, like I'm on the kind of amusement park ride that pushes you backwards in your seat. My mother suggested it could be linked to the supplement melatonin. I take 5 mg of sublingual melatonin a night to help me sleep. Have you ever heard of melatonin causing this type of dizziness?

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Big Belly May Expand Risk of Dementia

Having a big belly in middle age could increase your risk of dementia in old age, a study suggests. More than 6,500 men and women in their 40s were measured front to back using calipers. A distance of more than 10 inches was considered high. About 35 years later, nearly 1 in 6 people had developed Alzheimer’s disease or another form of dementia. People who had big bellies in their 40s were nearly twice as likely to have dementia. This was true even for people who had normal body weight but extra fat in the belly. Overweight people were even more likely to have dementia if their weight was concentrated in the belly. The Associated Press wrote about the study March 27. It was in the journal Neurology.

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CTs Can Find Risky Calcium in Arteries

A computed tomography (CT) scan can help predict the risk of a heart attack, a study finds. But it’s unclear if the scans are worth the cost, $300 to $600. Researchers gave CT scans to more than 6,700 men and women. They were white, black, Chinese and Hispanic. Some people’s scans showed large amounts of calcium in the walls of the heart arteries. They were 10 times more likely to have major heart events in the next four years as those with the least calcium in their arteries. Events included heart attacks, heart-related death, major chest pain and procedures to unblock heart arteries. HealthDay News wrote about the study March 26. It was published in the New England Journal of Medicine.

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Colo. Water System Disinfected

Crews in Alamosa, Colo., began flushing out the city’s water system with chlorine March 25, the Associated Press (AP) said. The purpose was to kill salmonella bacteria. Nearly 250 people have become ill from salmonella in the last couple of weeks. The bacteria can cause diarrhea, fever and stomach pain. Officials are not sure of the cause. They have ruled out contamination with wastewater. They also say the water was not tainted on purpose. People shouldn’t drink city water until the chlorine washes away, AP reported. This may take a few weeks. Bathing may be allowed in a few days.

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Survey: Drug Samples Don’t Cut Costs

People who get free drug samples may spend more, not less, on prescriptions, a study finds. The study used data on 5,709 people from a U.S. health survey. In two years, 14% received at least one free drug sample. In the six months before this, they spent an average of $166 on prescription drugs. They spent about $244 during the six months they got the sample and $212 in the next six months. People who didn’t get free samples spent about $178 in six months. HealthDay News reported on the study March 24. It was in the journal Medical Care.

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MMRV Vaccine No Longer Preferred

Health officials no longer recommend that preference be given to the four-vaccine combination called MMRV (measles, mumps, rubella, varicella). Although it requires two separate injections, rather than just one, the parents of children should first be offered the MMR vaccine and a separate varicella (chicken pox) shot. That’s because fever-related seizures are seen more often in children who receive MMRV instead of the two separate shots. The change was published in the Morbidity and Mortality Weekly Report on March 14.

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Home Tests Find Disease-Related Genes

A researcher who found gene mutations related to bipolar disorder now is selling a home test for the genes. This is the latest of more than 1,000 home gene tests for various conditions. The Associated Press reported on the home tests March 22. The new test looks for mutations in two genes. A person spits into a cup and sends the saliva to a laboratory. Results are sent to the person’s doctor. A positive result does not mean that someone has bipolar disorder. It means the risk of this disease is two to three times higher than average.

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Prostate Cancer: Looking Beyond Survival

Prostate cancer treatment affects each man differently. It also affects spouses and partners. Researchers studied 1,201 men and 625 of their spouses or partners. They found that certain treatments caused more quality-of-life issues. These included problems with sexual function, urination, mood/energy, and bowel function. These quality-of-life issues also often affected spouses and partners. The study is published in the March 20 issue of the New England Journal of Medicine.

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